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DUSP22抗原(重组蛋白)

价格: 在线咨询
货号:
KT011375
产品规格:
1mg
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

中文名称:DUSP22抗原(重组蛋白)


英文名称: DUSP22 Antigen (Recombinant Protein)


储      存: 冷冻(-20℃)


相关类别: 抗原


概述

 

Fusion protein corresponding to a region derived from 104-184 amino acids of human DUSP22

 

技术规格

 

Full name:

dual specificity phosphatase 22

Synonyms:

VHX; JKAP; JSP1; MKPX; JSP-1; MKP-x; LMWDSP2; LMW-DSP2

Swissprot:

Q9NRW4

Gene Accession:

BC016844

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes.

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