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产品详情
操作说明
注意事项
Product Information
|
Description |
GFAP mouse monoclonal |
|
Protein full name |
Glial fibrillary acidic protein |
|
Synonyms |
GFAP, ALXDRD, glial fibrillary acidic protein |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse GFAP |
|
Isotype |
IgG |
|
Predicted MW. |
49KDa |
|
Observed MW. |
49KDa |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Uniprot ID |
Applications
|
applications |
species |
dilution |
Positive tissue |
|
WB |
Mouse,Rat |
1:500-1:5000 |
brain, cerebral cortex, spinal cord |
|
IHC |
Mouse,Rat |
1:500-1:2000 |
brain |
|
IF |
Mouse,Rat |
1:500-1:2000 |
brain |
Background
Glial fibrillary acidic protein is an intermediate filament (IF) protein that is expressed by numerous cell types of the central nervous system (CNS) including astrocytes and ependymal cells.GFAP has also been found to be expressed in glomeruli and peritubular fibroblasts taken from rat kidneys Leydig cells of the testis in both hamsters and humans, human keratinocytes, human osteocytes and chondrocytes and stellate cells of the pancreas and liver in rats. It is closely related to its non-epithelial family members, vimentin,desmin, and peripherin, which are all involved in the structure and function of the cell’s cytoskeleton.
Images
|
|
Western blot analysis of GFAP (GB12096) at dilution of 1:1000 |
|
|
Immunohistochemistry analysis of paraffin-embedded mouse brain using GFAP (GB12096) at dilution of 1:1200 |
|
|
Immunohistochemistry analysis of paraffin-embedded rat brain using GFAP (GB12096) at dilution of 1:1200 |
|
Immunofluorescence analysis of paraffin-embedded mouse brain using GFAP (GB12096) at dilution of 1:1000 |
|
Immunofluorescence analysis of paraffin-embedded rat brain using GFAP (GB12096) at dilution of 1:1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
Publications:
|
|
Title |
Journal |
Pubmed ID |
Application |
|
1 |
Knockdown of T Cell Immunoglobulin and Mucin 1 (Tim-1) Suppresses Glioma Progression Through Inhibition of the Cytokine-PI3K/AKT Pathway. |
OncoTargets and therapy |
32801766 |
IF |
|
2 |
Activation of PPAR-β/δ Attenuates Brain Injury by Suppressing Inflammation and Apoptosis in a Collagenase-Induced Intracerebral Hemorrhage Mouse Model. |
Neurochemical Research |
31939088 |
IF |
|
3 |
LY354740 Reduces Extracellular Glutamate Concentration, Inhibits Phosphorylation of Fyn/NMDARs, and Expression of PLK2/pS129 α-Synuclein in Mice Treated With Acute or Sub-Acute MPTP. |
Frontiers in Pharmacology |
32180729 |
IF |
|
4 |
Differences in neurotropism and neurotoxicity among retrograde viral tracers. |
Molecular Neurodegeneration |
30736827 |
IF |
|
5 |
Cdc42-Dependent Transfer of mir301 from Breast Cancer-Derived Extracellular Vesicles Regulates the Matrix Modulating Ability of Astrocytes at the Blood-Brain Barrier. |
International Journal of Molecular Sciences |
32481745 |
|
|
6 |
Fushiming Capsule Attenuates Diabetic Rat Retina Damage via Antioxidation and Anti-Inflammation. |
Evidence-based Complementary and Alternative Medicine : Ecam |
31396288 |
|
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