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产品详情
操作说明
注意事项
Product Information
|
Description |
N Cadherin mouse monoclonal |
|
Protein full name |
Cadherin-2 |
|
Synonyms |
Neural cadherin, N-cadherin, CD325, CDw325, Cadherin 2 N cadherin neuronal, CDHN, Cdh2, Cadherin 2 type 1, NCAD, N cadherin 1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse N-cadherin |
|
Isotype |
IgG |
|
Subcellular location |
Membrane |
|
Predicted MW. |
100 kDa |
|
Observed MW. |
140 kDa |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 1000-1: 2000 |
colon, brain, cerebral cortex |
|
IHC |
Human, Mouse, Rat |
1: 1000-1: 2000 |
colon |
|
IF |
Human, Mouse, Rat |
1: 500-1: 1000 |
colon |
Background
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.
Images
|
Western blot analysis of N Cadherin (GB12135) at dilution of 1: 1000 |
|
Immunohistochemistry analysis of paraffin-embedded human colon using N Cadherin (GB12135) at dilution of 1: 1500
|
|
|
Immunohistochemistry analysis of paraffin-embedded mouse colon using N Cadherin (GB12135) at dilution of 1: 1500 |
|
Immunohistochemistry analysis of paraffin-embedded rat colon using N Cadherin (GB12135) at dilution of 1: 1500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室