服务热线
400-1016-218
联系方式
- 手机：400-1016-218
- Q Q：355185756
- 邮箱：355185756@qq.com
- 地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室
Anti -Tyrosine Hydroxylase Mouse mAb
价格：
在线咨询
货号：
DRF101 367
产品规格：
100 μL
Applications：
Species：
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
| Description |
Tyrosine Hydroxylase mouse monoclonal |
| Protein full name |
Tyrosine 3-monooxygenase |
|
Synonyms |
TH, Th, DYT14, DYT5b, TYH, tyrosine hydroxylase, Tyrosine hydroxylase |
| Immunogen | Recombinant protein corresponding to Mouse Tyrosine Hydroxylase |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location |
cytoplasm, axon |
| Uniprot ID |
P24529,P04177 |
Applications
| Applications |
IHC |
IF |
| Species |
Mouse,Rat |
Mouse,Rat |
| Dilution |
1:1000-1:3000 |
1:500-1:2000 |
| Positive tissue |
Brain, substantia nigra |
Mouse striatum |
Background
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA). It does so using molecular oxygen(O2), as well as iron (Fe2+) and tetrahydrobiopterin as cofactors. L-DOPA is a precursor for dopamine, which, in turn, is a precursor for the important neurotransmitters norepinephrine (noradrenaline) and epinephrine(adrenaline). Tyrosine hydroxylase catalyzes the rate limiting step in this synthesis of catecholamines. In humans, tyrosine hydroxylase is encoded by the TH gene,and the enzyme is present in the central nervous system (CNS), peripheral sympathetic neurons and the adrenal medulla.Tyrosine hydroxylase, phenylalanine hydroxylase and tryptophan hydroxylase together make up the family of aromatic amino acid hydroxylases(AAAHs).
Images
|
|
Immunofluorescence analysis of paraffin-embedded rat brain using Tyrosine Hydroxylase (GB12181) at dilution of 1:1000 |
|
|
Immunohistochemistry analysis of paraffin-embedded rat substantia nigra using Tyrosine Hydroxylase (GB12181) at dilution of1:3000 |
|
|
Immunohistochemistry analysis of paraffin-embedded mouse striatum using Tyrosine Hydroxylase (GB12181) at dilution of 1:3000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.
凡合肥万物生物科技有限公司销售的产品均有严格的质量保证。如发现产品存在包装规格疑问，请于收货之日起七日内向我公司总部或当地办事处提出，并请保证该产品，以备本公司进行核对检验。如果发现有质量问题，请于收货后一月内保留产品50%以上的量，以便本公司回收产品进行质检，确认产品质量。如逾期，则视为已经对本公司产品进行验收。 声明：如发生产品索赔事宜，本公司仅在产品价格范围内酌情赔偿，恕不接受超出产品价格范围之赔偿。客户在使用过程中有任何技术问题可以拨打技术售后服务电话我们随时给予解答。
合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室