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产品详情
操作说明
注意事项
Product Information
| Description |
BMP2 mouse monoclonal |
| Protein full name |
Bone morphogenetic protein 2 |
|
Synonyms |
BMP2, BDA2, BMP2A,bone morphogenetic protein 2 |
| Immunogen | Recombinant protein corresponding to Mouse BMP2 |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location |
Secreted |
| Uniprot ID |
Applications
| Applications | IHC,IF |
| Species |
Rat |
| Dilution |
1:500-1:1000 |
| Positive tissue |
bone |
Background
Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.
Images
|
|
Immunohistochemistry analysis of paraffin-embedded rat bone using BMP2 (GB12252) at dilution of 1:1000 |
|
|
Immunohistochemistry analysis of paraffin-embedded rat bone using BMP2 (GB12252) at dilution of 1:1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室