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产品详情
操作说明
注意事项
Product Information
|
Description |
HSP90 mouse monoclonal |
|
Protein full name |
Heat shock protein HSP 90-alphav |
|
Synonyms |
HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP-2, LAP2, HEL-S-65p, Heat shock protein 90kDa alpha |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse HSP90A |
|
Isotype |
IgG |
|
Subcellular location |
|
|
Predicted MW. |
90 kDa |
|
Observed MW. |
90 kDa |
|
Purity |
Affinity purification |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Ttissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain, testis |
|
IHC |
Mouse, Rat |
1: 500-1: 1000 |
testis, ovary, brain, colon |
| IF | Mouse, Rat | 1: 500-1: 1000 |
|
Background
Complemented by the constitutively expressed paralog Hsp90B which shares over 85% amino acid sequence identity, Hsp90A expression is initiated when a cell experiences proteotoxic stress. Once expressed Hsp90A dimers operate as molecular chaperones that bind and fold other proteins into their functional 3-dimensional structures. This molecular chaperoning ability of Hsp90A is driven by a cycle of structural rearrangements fueled by ATP hydrolysis. Current research on Hsp90A focuses in its role as a drug target due to its interaction with a large number of tumor promoting proteins and its role in cellular stress adaptation.
Images
|
|
Western blot analysis of HSP90 (GB12284) at dilution of 1: 1000
|
|
Immunohistochemistry analysis of paraffin-embedded mouse testis using HSP90 (GB12284) at dilution of 1: 1000 |
|
Immunohistochemistry analysis of paraffin-embedded rat testis using HSP90 (GB12284) at dilution of 1: 1000 |
|
Immunohistochemistry analysis of paraffin-embedded mouse ovary using HSP90 (GB12284) at dilution of 1: 1000 |
|
Immunohistochemistry analysis of paraffin-embedded rat ovary using HSP90 (GB12284) at dilution of 1: 1000 |
|
Immunohistochemistry analysis of paraffin-embedded mouse brain using HSP90 (GB12284) at dilution of 1: 1000 |
|
Immunohistochemistry analysis of paraffin-embedded rat brain using HSP90 (GB12284) at dilution of 1: 1000 |
|
Immunohistochemistry analysis of paraffin-embedded rat colon using HSP90 (GB12284) at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室