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Anti -MEK1 Mouse mAb

价格: 在线咨询
货号:
DRF101394
产品规格:
100 μL
Applications:
Species:
购买数量:
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产品详情 操作说明 注意事项

Product Information


Description

MEK1 mouse monoclonal

Protein full name

Dual specificity mitogen-activated protein kinase kinase 1

Synonyms

MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1,mitogen activated protein kinase kinase 1, ERK activator kinase 1, MAP kinase kinase 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse MEK1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

43 kDa

Observed MW.

45 kDa

Uniprot ID

Q02750, Q01986, P31938




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 1000-1: 2000

lung, kidney




Background



The protein is a member of the dual-specificity protein kinase family that acts as amitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon activation by a wide variety of extra- and intracellular signals. As an essential component of the MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.




Images



image.png

Western blot analysis of MEK1

(GB12305) at dilution of 1: 1000

Lane 1: Hela cell lysate

Lane 2: HepG2 cell lysate

Lane 3: A431 cell lysate

Lane 4: NIH/3T3 cell lysate

Lane 5: PC12 cell lysate

Lane 6: Mouse lung tissue lysate

Lane 7: Mouse kidney tissue lysate

Lane 8: Rat kidney tissue lysate

Lane 9: Rat lung tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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