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Anti -TNF Alpha Mouse mAb

价格: 在线咨询
货号:
DRF101448
产品规格:
50 μL
Applications:
Species:
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

TNF Alpha mouse monoclonal

Protein full name

Tumor necrosis factor alpha

Synonyms

TNF, DIF, TNF-alpha, TNFA, TNFSF2, Tumour necrosis factor,  Tumour necrosis factor alpha, TNF-α, tumor necrosis factor, TNLG1

Immunogen

Recombinant protein corresponding to Human TNF α

Isotype IgG
Purity Affinity purification

Predicted MW.

26 kDa

Observed MW.

26 kDa

Subcellular location

Cell membrane,Secreted

Uniprot ID

P01375, P06804, P16599




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse

1: 2000-1: 5000

LPS treated RAW 264.7 cells, HeLa cells,HL-60 cells, PC-12 cells

IHC

Human

1: 200-1: 1000

breast cancer, colon cancer, liver cancer

IF

Human

1: 50-1: 500

breast cancer




Background


Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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