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产品详情
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注意事项
Product Information
| Gene Name | FSCN1 FAN1 HSN SNL |
| Protein Name | Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55) |
| Human Gene Id | 6624 |
| Human Swiss Prot No | Q16658 |
| Immunogen | Synthesized peptide derived from human Fascin |
| Specificity | This antibody detects endogenous levels of human Fascin |
| Source | Mouse/IgG1, Kappa |
| Concentration | 1 mg/ml |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Applications
| Applications | Species | Dilution |
|
| IHC、IF | Human | 1:200-1:500 |
|
Background
fascin actin-bundling protein 1(FSCN1) Homo sapiens This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011],
Images
|
Immunohistochemical analysis of paraffin-embedded Classical Hodgkin's lymphoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. |
|
Immunohistochemical analysis of paraffin-embedded Classical Hodgkin's lymphoma. 1, Antibody was diluted at 1:200(4°,overnight). 2, Tris-EDTA,pH8.0 was used for antigen retrieval. |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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