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产品详情
操作说明
注意事项
Product Information
|
Description |
CXCR1 rabbit polyclonal |
|
Protein full name |
C-X-C chemokine receptor type 1 |
|
Synonyms |
CXCR1, C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA, Interleukin 8 receptor, C-X-C motif chemokine receptor 1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CXCR1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cell membrane |
|
Predicted MW. |
40 kDa |
|
Observed MW. |
45 kDa |
|
Uniprot ID |
P25024, Q810W6, P70612 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
pneumonia, splenitis |
|
IHC |
Human, Mouse, Rat |
1: 1000-1: 4000 |
spleen，immune spleen |
|
IF |
Human, Mouse, Rat |
1: 500-1: 1000 |
spleen，immune spleen |
Background
CXCR1 is a chemokine receptor, which is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein-activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. Stimulation of CXCR1 in neutrophils by its primary ligand, Interleukin 8, leads to neutrophil chemotaxis and activation.
Images
|
Western blot analysis of CXCR1 at dilution of 1: 1000 Lane 1: HeLa cell lysate Lane 2: HepG2 cell lysate Lane 3: Jurkat cell lysate Lane 4: A20 cell lysate Lane 5: Raw264.7 cell lysate Lane 6: Mouse splenitis tissue lysate Lane 7: Mouse pneumonia tissue lysate Lane 8: Rat splenitis tissue lysate Lane 9: Rat pneumonia tissue lysate
|
|
Immunohistochemistry analysis of paraffin-embedded mouse spleen using CXCR1 at dilution of 1: 1000
|
|
Immunohistochemistry analysis of paraffin-embedded mouse immune spleen using CXCR1 at dilution of 1: 1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室