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Anti -LEF1 Rabbit pAb

价格: 在线咨询
货号:
DRF101949
产品规格:
100 μL
Applications:
Species:
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information



Description

LEF1 rabbit polyclonal

Protein full name

Lymphoid enhancer-binding factor 1

Synonyms

LEF-1, Lef1, TCF1 alpha, TCF1ALPHA, TCF7L3, FLJ46390, TCF10, LEF1

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse LEF1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

P27782, Q9QXN1





Applications



Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 900-1: 1800

thymus

IF

Mouse, Rat

1: 600-1: 1200

thymus, spleen





Background


This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.




Images


Immunohistochemistry analysis of paraffin-embedded mouse thymus using

LEF1 (GB111887) at dilution of 1: 1800

Immunohistochemistry analysis of paraffin-embedded rat thymus using

LEF1 (GB111887) at dilution of 1: 1800

Immunofluorescent analysis of paraformaldehyde-fixed mouse spleen using

LEF1 (GB111887) at dilution of 1: 1200

Immunofluorescent analysis of paraformaldehyde-fixed mouse thymus using LEF1 (GB111887) at dilution of 1: 1200

Immunofluorescent analysis of paraformaldehyde-fixed rat thymus using

LEF1 (GB111887) at dilution of 1: 1200




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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