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Anti -Metabotropic Glutamate Receptor 5 Rabbit pAb
价格：
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货号：
KT011498
产品规格：
100 μL
Applications：
WB
Species：
H
购买数量：
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400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
Metabotropic Glutamate Receptor 5 antibody |
|
Protein full name |
Metabotropic glutamate receptor 5 |
|
Synonyms |
Grm5, Metabotropic Glutamate Receptor 5, GRM5, GPRC1E, MGLUR5, PPP1R86, MGlu5 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human Metabotropic Glutamate Receptor 5 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
128 kDa |
|
Observed MW. |
128 kDa |
|
Uniprot ID |
Q3UVX5, P31424 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human |
1: 500-1: 1000 |
HeLa, SH-SY5Y |
Background
The amino acid L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacological properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7, and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Images
|
Western blot analysis of mGLuR5 (GB11746) at dilution of 1: 500
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室
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