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Anti -Torsin A/DYT1 Rabbit pAb

价格: 在线咨询
货号:
KT011517
产品规格:
100 μL
Applications:
WB/IHC/IF
Species:
HR/HR/HR
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Torsin A rabbit polyclonal

Protein full name

Torsin-1A

Synonyms

Dystonia 1 protein, Torsin ATPase 1, Torsin family 1 member A, Tor1a, Dyt1, Torsin A

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Torsin A

Isotype

IgG

Purity

Affinity purification

Subcellular location

CytoplasmNucleus

Predicted MW.

38 kDa

Observed MW.

38 kDa

Uniprot ID

O14656Q9ER39Q68G38




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

kidney, liver

IHC

Human, Rat

1: 800-1: 1600

colon cancer, ovary cancer, esophageal cancer, testis

IF

Human, Rat

1: 1500-1: 3000

brain nigra




Background


TOR1A (torsin A), also known as DYT1 is a member of the AAA family of adenosine triphosphatases (ATPases) that mediate chaperone and other functions involved in conformational modeling of proteins, protection from stress, and targeting of proteins to cellular organelles. TOR1A primarily localizes to the ER while exposure to oxidative stress causes the redistribution to cell surface protrusions. Mutations in gene encoding TOR1A cause the most severe form of hereditary dystonia, termed early onset, generalized dystonia.




Images


Western blot analysis of Torsin A (GB111294) at dilution of 1: 1000
Lane 1: Mouse kidney tissue lysate
Lane 2: Mouse liver tissue lysate
Lane 3: Rat liver tissue lysate

Immunohistochemistry analysis of paraffin-embedded human colon cancer using Torsin A (GB111294) at dilution of 1: 800


Immunohistochemistry analysis of paraffin-embedded human ovary cancer using Torsin A (GB111294) at dilution of 1:800

Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using Torsin A (GB111294) at dilution of 1: 800

Immunohistochemistry analysis of paraffin-embedded rat testis using Torsin A (GB111294) at dilution of 1: 800



Immunofluorescent analysis of paraformaldehyde-fixed rat brain nigra using Torsin A (GB111294) at dilution of 1: 3000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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