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产品详情
操作说明
注意事项
Product Information
| Description | TAU rabbit polyclonal |
| Protein full name | Microtubule-associated protein tau |
| Synonyms | Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, DDPAC, FTDP 17, MAPTL, RNPTAU, PPP1R103, Paired helical filament-tau |
| Immunogen |
KLH conjugated Synthetic peptide corresponding to Human TAU |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Cytoplasm, Cell membrane |
| Predicted MW. | 79 kDa |
| Observed MW. | 50-80 kDa |
| Uniprot ID | P10636, P10637, P19332 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 2000-1: 4000 | brain, cortex, spinal cord, hippocampus |
| IHC | Human, Mouse | 1: 3000-1: 5000 | gliomas, brain |
Background
Tau is a neuronal microtubule-associated protein found predominantly on axons. The function of Tau is to promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome.
Images
|
Western blot analysis of TAU (GB111608) at dilution of 1: 2000 Lane 1: Human glioma cell lysate Lane 2: Mouse brain tissue lysate Lane 3: Mouse cortex tissue lysate Lane 4: Mouse hippocampus tissue lysate Lane 5: Mouse spinal cord tissue lysate Lane 6: Rat brain tissue lysate Lane 7: Rat cortex tissue lysate Lane 8: Rat hippocampus tissue lysate |
|
Immunohistochemistry analysis of paraffin-embedded human gliomas using TAU (GB111608) at dilution of 1: 3000 |
|
Immunohistochemistry analysis of paraffin-embedded mouse brain using TAU (GB111608) at dilution of 1: 3000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
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地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室