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Anti -Synphilin 1 Rabbit pAb

价格: 在线咨询
货号:
KT011530
产品规格:
100 μL
Applications:
WB/IHC/IF
Species:
MR/MR
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Synphilin 1 rabbit polyclonal antibody

Protein full name

Synphilin-1

Synonyms

Alpha-synuclein-interacting protein, Sncaip, Sph1, Synuclein alpha interacting protein

Immunogen

Recombinant protein corresponding to Mouse Synphilin 1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Predicted MW.

106 kDa

Observed MW.

72 kDa

Uniprot ID

Q99ME3




Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 500-1: 1000

heart, brain, placenta

IHC/IF

Mouse, Rat

1: 400-1: 2000

brain, heart




Background


This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of only two have been determined.




Images


Picture 1.png

Western blot analysis of Sncaip (GB111991) at dilution of 1: 500

Picture 2.png

Immunohistochemistry of paraffin embedded mouse brain using Sncaip (GB111991) at dilution of 1: 650 (300x lens)

Picture 3.png Immunohistochemistry of paraffin embedded mouse heart using Sncaip (GB111991) at dilution of 1: 400 (400x lens)

Picture 4.png

Immunohistochemistry of paraffin embedded rat brain using Sncaip (GB111991) at dilution of 1: 400 (200x lens)

Picture 5.png

Immunohistochemistry of paraffin embedded rat heart using Sncaip (GB111991) at dilution of 1: 650 (200x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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