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Anti -Seladin 1 Rabbit pAb
价格：
在线咨询
货号：
KT011547
产品规格：
100 μL
Applications：
WB/IHC/IF
Species：
H/MR
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
Seladin 1 rabbit polyclonal antibody |
|
Protein full name |
Delta(24)-sterol reductase |
|
Synonyms |
24-dehydrocholesterol reductase, 3-beta-hydroxysterol Delta-24-reductase, Diminuto/dwarf1 homolog, Seladin-1, DHCR24, KIAA0018 |
|
Immunogen |
Recombinant protein corresponding to Mouse Seladin 1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm |
|
Predicted MW. |
60 kDa |
|
Observed MW. |
60 kDa |
|
Uniprot ID |
Q15392, Q8VCH6, Q5BQE6 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human |
1: 500-1: 1000 |
HT-29, HeLa |
|
IHC/IF |
Mouse, Rat |
1: 500-1: 3000 |
colon, duodenum, liver, lung, small intestine |
Background
The Seladin 1 encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. Protects cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis.Missense mutations in this gene have been associated with desmosterolosis.
Images
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Western blot analysis of Dhcr24 (GB112463) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded mouse duodenum using Dhcr24 (GB112463) at dilution of 1: 650 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse liver using Dhcr24 (GB112463) at dilution of 1: 1300 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lung using Dhcr24 (GB112463) at dilution of 1: 1300 (400x lens) |
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Immunohistochemistry of paraffin embedded rat colon using Dhcr24 (GB112463) at dilution of 1: 650 (400x lens) |
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Immunohistochemistry of paraffin embedded rat liver using Dhcr24 (GB112463) at dilution of 1: 1300 (400x lens) |
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Immunohistochemistry of paraffin embedded rat lung using Dhcr24 (GB112463) at dilution of 1: 1300 (400x lens) |
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Immunohistochemistry of paraffin embedded rat small intestine using Dhcr24 (GB112463) at dilution of 1: 650 (400x lens) |
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Immunofluorescence of paraffin embedded mouse duodenum using Dhcr24 (GB112463) at dilution of 1: 650 (400x lens) |
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Immunofluorescence of paraffin embedded mouse lung using Dhcr24 (GB112463) at dilution of 1: 650 (400x lens) |
|
|
Immunofluorescence of paraffin embedded rat duodenum using Dhcr24 (GB112463) at dilution of 1: 650 (400x lens) |
|
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Immunofluorescence of paraffin embedded rat lung using Dhcr24 (GB112463) at dilution of 1: 650 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
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地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室