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Anti -Alpha-synuclein Rabbit pAb

价格: 在线咨询
货号:
KT011561
产品规格:
100 μL
Applications:
WB/IHC/ICC
Species:
MR/HMR/H
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Alpha-synuclein rabbit polyclonal

Protein full name

Alpha-synuclein

Synonyms

Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, Snca, Syn

Immunogen

Recombinant protein corresponding to

Mouse Alpha-synuclein

Isotype

IgG

Purity

Affinity purification

Subcellular location

NucleusSecretedCytoplasm, Cell membrane

Predicted MW.

14 kDa

Observed MW.

18 kDa

Uniprot ID

O55042P37377



Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

hippocampus

IHC

Human, Mouse, Rat

1: 1500-1: 3000

cerebellum

ICC

Human

1: 800-1: 1600

SH-SY5Y



Background


Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. 




Images


Western blot analysis of Snca (GB112945) 

at dilution of 1: 1000

Lane 1: Mouse hippocampus tissue lysate

Lane 2: Rat hippocampus tissue lysate

Immunohistochemistry analysis of paraffin-embedded human oligodendrocytoma using Snca (GB112945) at dilution of 1: 3000

Immunohistochemistry analysis of paraffin-embedded mouse brain using 

Snca (GB112945) at dilution of 1: 3000

Immunohistochemistry analysis of paraffin-embedded rat brain using Snca (GB112945) at dilution of 1: 3000

Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using Snca (GB112945) at dilution of 1: 3000

Immunohistochemistry analysis of paraffin-embedded rat cerebellum using Snca (GB112945) at dilution of 1: 3000


IImmunocytochemistry analysis of 4% paraformaldehyde-fixed SH-SY5Y cells using Alpha-synuclein GB112945 at dilution of 1: 1400




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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