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Anti -GDNF Receptor alpha 2/GFRA2 Rabbit pAb
价格：
在线咨询
货号：
KT011675
产品规格：
100ul
Applications：
WB
Species：
H/M/R
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
GDNF Receptor alpha 2/GFRA2 rabbit polyclonal antibody |
|
Protein full name |
GDNF family receptor alpha-2 |
|
Synonyms |
GDNF receptor alpha-2, GDNFR-alpha-2, GFR-alpha-2, GDNF receptor beta, GDNFR-beta, Neurturin receptor alpha, NTNR-alpha, Gfra2, Gdnfrb, Trnr2 |
|
Immunogen |
Recombinant protein corresponding to Mouse GDNF Receptor alpha 2/GFRA2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
52 kDa |
|
Observed MW. |
52 kDa |
|
Uniprot ID |
O00451, O08842 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain, placenta, liver |
Background
GFRA2, also named as GDNFRB, RETL2 and TRNR2, belongs to the GDNFR family. It is a receptor for neurturin. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It is a potent survival factor for central dopaminergic neurons, motor neurons, and several other populations of neurons in the central and peripheral nervous systems. The GDNF signal is mediated by a complex of the receptor tyrosine kinase RET and a glycosylphosphatidylinositol (GPI)-linked protein, GDNFRA. GFRA2 has three isoforms with MW 34-36 kDa, 39-41 kDa and 50-55 kDa. This antibody recognizes all the three isoforms.
Images
|
|
Western blot analysis of GDNFReceptora2 (GB111764) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室