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Anti -GAD65 Mouse mAb
价格：
在线咨询
货号：
KT011779
产品规格：
100 μL
Applications：
WB/IHC/IF
Species：
H/M/R,M/R,M/R
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
GAD65 mouse monoclonal antibody |
|
Protein full name |
Glutamate decarboxylase 2 |
|
Synonyms |
GAD2, GAD65, glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, DCE 2, Glutamic Acid Decarboxylase 2; Glutamic Acid Decarboxylase 65 |
|
Immunogen |
Recombinant protein corresponding to Mouse GAD65 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
65 kDa |
|
Observed MW. |
65 kDa |
|
Uniprot ID |
Q05329, Q05683, P48320 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1:500-1:1000 |
brain, cerebral cortex, hippocampus, cerebellum |
|
IHC/IF |
Mouse, Rat |
1:500-1:2000 |
brain, cerebellum, epencephalon |
Background
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Images
|
Western blot analysis of GAD65 (GB12562) at dilution of 1: 1000 |
|
Immunohistochemistry of paraffin embedded mouse cerebellum using GAD65 (GB12562) at dilution of (300x lens) |
|
Immunohistochemistry analysis of paraffin-embedded mouse brain using GAD65 (GB12562) at dilution of 1: 1000(350x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室