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Anti -GDF 5 Rabbit pAb
价格：
在线咨询
货号：
KT011850
产品规格：
100 μL
Applications：
WB/IF
Species：
H/M,H/R,H/R
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
GDF 5 rabbit polyclonal |
|
Protein full name |
Growth/differentiation factor 5 |
|
Synonyms |
GDF-5, Bone morphogenetic protein 14, BMP-14, Gdf5, Bmp14, Bp, Gdf-5 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse GDF 5 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
55 kDa |
|
Observed MW. |
55 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse |
1: 500-1: 1000 |
NIH3T3, U87-MG |
| IF | Human, Rat | 1:200-1:400 |
|
Background
Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction . Secondly, negatively regulates chondrogenic differentiation through its interaction with NOG . Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 .
Images
|
Western blot analysis of GDF 5 (GB112138) at dilution of 1: 1000 Lane 1: NIH3T3 cell lysate Lane 2: U87-MG cell lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室