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Anti -CBX2 Rabbit pAb

价格: 在线咨询
货号:
KT012194
产品规格:
100 μL
Applications:
WB
Species:
HMR
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

CBX2 rabbit polyclonal antibody

Protein full name

Chromobox protein homolog 2

Synonyms

M33, Modifier 3 protein, Cbx2, CDCA6, MOD2, SRXY5, Polycomb

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse CBX2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

55 kDa

Observed MW.

55 kDa

Uniprot ID

Q14781, P30658




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

liver, spleen, testis




Background


Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development . PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility  . Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3) . Plays a role in the lineage differentiation of the germ layers in embryonic development . Involved in sexual development, acting as activator of NR5A1 expression .




Images


Picture 1.png

Western blot analysis of CBX2 (GB112013) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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