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产品详情
操作说明
注意事项
Product Information
|
Description |
L1CAM rabbit polyclonal antibody |
|
Protein full name |
Neural cell adhesion molecule L1 |
|
Synonyms |
NCAM-L1, CD171, L1cam, Caml1, L1-NCAM, HSAS, Hyd |
|
Immunogen |
Recombinant protein corresponding to Human L1CAM |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
141 kDa |
|
Observed MW. |
220 kDa |
|
Uniprot ID |
P11627, Q05695 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
brain, cerebellum, cerebral cortex |
Background
L1cam (L1 cell adhesion molecule isoform 1 precursor) is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
Images
|
|
Western blot analysis of CD171 (GB111218) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室