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产品详情
操作说明
注意事项
Product Information
|
Description |
alpha Actinin rabbit polyclonal |
|
Protein full name |
Alpha-actinin-1 |
|
Synonyms |
Alpha-actinin cytoskeletal isoform, F-actin cross-linking protein, actinin, Non-muscle alpha-actinin-1, ACTN1, actinin 1 smooth muscle, Actn1a, BDPLT15, I79_004057 |
|
Immunogen |
Recombinant protein corresponding to Mouse α-actinin1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
103 kDa |
|
Observed MW. |
103 kDa |
|
Uniprot ID |
Q7TPR4, P12814, Q9Z1P2 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 2000-1: 4000 |
lung, stomach, colon, hysteromyoma |
Background
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found alongmicrofilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene.
Images
|
|
Western blot analysis of α-actinin (GB11230) at dilution of 1: 2000. Lane 1: HepG2 cell lysate Lane 2: AN3CA cell lysate Lane 3: Human hysteromyoma tissue lysate Lane 4: Mouse lung tissue lysate Lane 5: Mouse stomach tissue lysate Lane 6: Mouse colon tissue lysate Lane 7: Rat lung tissue lysate Lane 8: Rat stomach tissue lysate Lane 9: Rat colon tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
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地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室