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Anti -CXCL16 Rabbit pAb

价格: 在线咨询
货号:
DRF101705
产品规格:
100 μL
Applications:
Species:
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

CXCL16 rabbit polyclonal

Protein full name

C-X-C motif chemokine 16

Synonyms

Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, Srpsox,  SR-PSOX, Small-inducible cytokine B16, Transmembrane chemokine CXCL16, CXCL16

Immunogen

Recombinant protein corresponding to

Mouse CXCL16

Isotype

IgG

Purity

Affinity purification

Predicted MW.

27 kDa

Observed MW.

28-35 kDa

Uniprot ID

Q8BSU2, Q6AXU5




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

lung, lymph node, stomach




Background


CXCL16 belongs to the CXC chemokine family, which is synthesised in plasmacytoid dendritic cell as a transmembrane molecule. It exists in a transmembrane and soluble form. The transmembrane form of CXCL16 functions as an adhesion molecule for CXCR6-expressing cells, whereas the soluble form of CXCL16 mediates infiltration of circulating cells into sites of injury. CXCL16, has been proposed as an important pathogenic mediator in inflammatory diseases, including rheumatoid arthritis, glomerulonephritis, or prostate cancer. CXCL16 has been implicated in some forms of renal disease such as lupus nephritis and antiglomerular basement membrane nephritis. CXCL16 also plays a pivotal role in the pathogenesis of angiotensin II–induced renal injury and fibrosis through regulation of macrophage and T cell infiltration and bone marrow–derived fibroblast accumulation.




Images


Western blot analysis of CXCL16 (GB111441)
at dilution of 1: 1000
Lane 1: Mouse lung tissue lysate
Lane 2: Mouse lymph node tissue lysate
Lane 3: Mouse stomach tissue lysate
Lane 4: Rat lung tissue lysate
Lane 5: Rat lymph node tissue lysate
Lane 6: Rat stomach tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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