服务热线
400-1016-218
联系方式
- 手机：400-1016-218
- Q Q：355185756
- 邮箱：355185756@qq.com
- 地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
Tollip rabbit polyclonal |
|
Protein full name |
Toll-interacting protein |
|
Synonyms |
TOLLIP, IL-1RAcPIP, toll interacting protein |
|
Immunogen |
Recombinant protein corresponding to Mouse Tollip |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Predicted MW. |
30 kDa |
|
Observed MW. |
30 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1 :500-1: 1000 |
brain, spleen, thymus |
|
IHC |
Human, Mouse, Rat |
1: 1000-1: 2000 |
liver cancer, spleen, brain, kidney, lung |
|
IF |
Human, Mouse, Rat |
1: 500-1: 1000 |
liver cancer, spleen, brain, kidney, lung |
Background
The Tollip is the component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates. The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates
Images
|
|
Western blot analysis of NCR1 (GB111102) at dilution of 1: 1000 |
|
|
Immunohistochemistry analysis of paraffin-embedded human liver cancer using Tollip (GB111093) at dilution of 1: 2000 |
|
|
Immunohistochemistry analysis of paraffin-embedded mouse spleen using Tollip (GB111093) at dilution of 1: 2000 |
|
|
Immunohistochemistry analysis of paraffin-embedded rat kidney using Tollip (GB111093) at dilution of 1: 2000 |
|
|
Immunohistochemistry analysis of paraffin-embedded rat brain using Tollip (GB111093) at dilution of 1: 2000 |
|
|
Immunohistochemistry analysis of paraffin-embedded rat lung using Tollip (GB111093) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
凡合肥万物生物科技有限公司销售的产品均有严格的质量保证。如发现产品存在包装规格疑问，请于收货之日起七日内向我公司总部或当地办事处提出，并请保证该产品，以备本公司进行核对检验。如果发现有质量问题，请于收货后一月内保留产品50%以上的量，以便本公司回收产品进行质检，确认产品质量。如逾期，则视为已经对本公司产品进行验收。 声明：如发生产品索赔事宜，本公司仅在产品价格范围内酌情赔偿，恕不接受超出产品价格范围之赔偿。客户在使用过程中有任何技术问题可以拨打技术售后服务电话我们随时给予解答。
合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室