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Anti -TLR4 Rabbit pAb

价格: 在线咨询
货号:
DRF101744
产品规格:
100 μL
Applications:
Species:
购买数量:
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产品详情 操作说明 注意事项

Product Information


Description

TLR4 rabbit polyclonal

Protein full name

Toll-like receptor 4

Synonyms

TLR4, ARMD10, CD284, TLR-4, TOLL,

toll like receptor 4

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse TLR4

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane

Uniprot ID

O00206, Q9QUK6, Q9QX05




Applications


applications

species

dilution

Positive tissue

IHC

Human, Rat

1: 500-1: 1000

tonsil, spleen

Lymph node

IF

Human, Rat

1: 500-1: 1000

tonsil, spleen

Lymph node




Background


TLR4 is a transmembrane protein, member of the toll-like receptor family, which belongs to the pattern recognition receptor (PRR) family. Its activation leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system.It is most well known for recognizinglipopolysaccharide (LPS), a component present in many Gram-negative bacteria (e.g. Neisseria spp.) and selectGram-positive bacteria. Its ligands also include several viral proteins, polysaccharide, and a variety of endogenous proteins such as low-density lipoprotein, beta-defensins, and heat shock protein.




Images



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Immunohistochemistry analysis of paraffin-embedded human tonsil using TLR4(GB11186) at dilution of 1:1000

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Immunohistochemistry analysis of paraffin-embedded rat lymph node using TLR4(GB11186) at dilution of 1:1000


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Immunohistochemistry analysis of paraffin-embedded rat spleen using TLR4(GB11186) at dilution of 1:1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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