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Anti -TLR9 Rabbit pAb

价格: 在线咨询
货号:
DRF101752
产品规格:
100 μL
Applications:
Species:
购买数量:
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产品详情 操作说明 注意事项

Product Information


Description

TLR9 rabbit polyclonal

Protein full name

Toll-like receptor 9

Synonyms

TLR9, CD289, toll like receptor 9, Toll like receptor 9 isoform A precursor, Toll like receptor 9 isoform B

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse TLR9

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Lysosome, Membrane

Uniprot ID

Q9EQU3, Q9NR96




Applications


applications

species

dilution

Positive tissue

IHC

Human, Mouse

1: 100-1: 500

tonsil, spleen

IF

Human, Mouse

1: 100-1: 500

tonsil, spleen




Background


Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response . Controls lymphocyte response to Helicobacter infection (By similarity).




Images



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Immunohistochemistry analysis of paraffin-embedded human tonsil using TLR9(GB11266) at dilution of 1:200

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Immunohistochemistry analysis of paraffin-embedded mouse spleen using TLR9(GB11266) at dilution of 1:400




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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