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Anti -TPX2 Rabbit pAb

价格: 在线咨询
货号:
KT011743
产品规格:
Applications:
WB | IHC | IF
Species:
H /H,M,R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

TPX2 rabbit polyclonal antibody

Protein full name

Targeting protein for Xklp2

Synonyms

Tpx2, DIL2, C20ORF1, C20orf2

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse TPX2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Predicted MW.

86 kDa

Observed MW.

100 kDa



Applications


Applications

Species

Dilution

Positive Sample

WB

Human

1: 500-1: 1000

K562, HT-29, MCF-7

IHC/IF

Human, Mouse, Rat

1: 200-1: 400

bone, colon, skin, testis




Background


TPX2 is an ortholog of the Targeting Protein for Xenopus kinesin-like protein 2 (XKLP2) and was originally named restricted expression/proliferation-associated protein 100 (REPP86). TPX2 regulates the Xenopus kinesin-like protein 2 which is a plus end-directed microtubule motor required for centrosome separation and maintenance of spindle polarity during mitosis. TPX2 activates mitotic serine-threonine Aurora A kinase, nucleates microtubules and is considered as a critical factor for spindle assembly in mammalian mitotic cells. It is actively transported into the nucleus during interphase via importin alpha/beta receptors and this nuclear import sequesters TPX2 away from cytoplasmic tubulin to prevent premature spindle assembly.




Images


Western blot analysis of TPX2 (GB111226) at dilution of 1: 500

Immunohistochemistry of paraffin embedded human colon using TPX2 (GB111226) at dilution of 1: 200 (400x lens)

Immunohistochemistry of paraffin embedded mouse skin using TPX2 (GB111226) at dilution of 1: 200 (400x lens)

Immunohistochemistry of paraffin embedded mouse testis using TPX2 (GB111226) at dilution of 1: 200 (400x lens)

Immunohistochemistry of paraffin embedded rat bone using TPX2 (GB111226) at dilution of 1: 200 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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