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Anti -Cdk9 Rabbit pAb

价格: 在线咨询
货号:
KT011788
产品规格:
100 μL
Applications:
IF
Species:
Rat
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information

Description

Cdk9 rabbit polyclonal

Protein full name

Cyclin-dependent kinase 9

Synonyms

Cell division protein kinase 9, Cdk9, C2k, CDC2L4, CTK1, PITALRE, TAK

Immunogen

Recombinant protein corresponding to Mouse Cdk9

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Uniprot ID

Q641Z4



Applications

Applications

Species

Dilution

Positive Tissue

IF

Rat

1: 500-1: 1000

brain



Background


CDK9 (cyclin-dependent kinase 9) is a member of the cyclin-dependent protein kinase family. It is involved in the regulation of transcription. CDK9 is a member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex. It regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors. CDK9 promotes RNA synthesis in genetic programs for cell growth, differentiation and viral pathogenesis. The CDK9/cyclin-K complex also has kinase activity towards CTD of RNAPII and can substitute for CDK9/cyclin-T P-TEFb in vitro. Chronic activation of CDK9 causes cardic myocyte enlargement leading to cardiac hypertrophy and confers a predisposition to heart failure.


Images

Immunohistochemistry analysis of paraffin-embedded rat brain using
Cdk9 (GB111389) at dilution of 1: 600


Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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