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产品详情
操作说明
注意事项
Product Information
|
Description |
RCC2 rabbit polyclonal antibody |
|
Protein full name |
Protein RCC2 |
|
Synonyms |
Rcc2, Kiaa1470, RCC1-like protein TD-60, TD-60, Telophase disk protein of 60 kDa, 2610510H01Rik, 2610529N02Rik, AA536646, AA675016, KIAA1470, mKIAA1470 |
|
Immunogen |
Recombinant protein corresponding to Mouse RCC2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
56 kDa |
|
Observed MW. |
60 kDa |
|
Uniprot ID |
Q9P258, Q8BK67 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
brain, cerebral cortex |
Background
RCC2 (regulator of chromosome condensation 2) is a member of the RCC1 family of guanine nucleotide exchange factors. RCC2 has been identified as part of the chromosomal passenger complex (CPC) which coordinates the chromosomal and cytoskeletal events of mitosis. Chromosomal passengers are proteins present in complexes with aurora B, inner centromeric protein (INCENP), survivin, and borealin. RCC2 has been demonstrated to be required for the recruitment of survivin and aurora B and is essential for proper chromosome segregation and the completion of cell cleavage. Loss of RCC2 inhibits spindle assembly, activates the spindle assembly checkpoint, and blocks cells in prometaphase.
Images
|
Western blot analysis of RCC2 (GB111530) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室