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产品详情
操作说明
注意事项
Product Information
|
Description |
p27 KIP1 rabbit polyclonal antibody |
|
Protein full name |
Cyclin-dependent kinase inhibitor 1B |
|
Synonyms |
CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1, cyclin-dependent kinase inhibitor 1B, cyclin dependent kinase inhibitor 1B |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse p27 KIP1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Nucleus, Cytoplasm, Endosome |
|
Uniprot ID |
P46527, P46414 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Human, Mouse, Rat |
1: 100-1: 500 |
colon, heart, hepatitis, nephritis, pneumonia, Skeletal muscle, stomach, subcutaneous transplant tumor |
Background
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
Images
|
Immunohistochemistry of paraffin embedded human stomach using P27 (GB11154) at dilution of 1:400 (400x lens) |
|
Immunohistochemistry of paraffin embedded human subcutaneous transplant tumor using P27 (GB11154) at dilution of 1:400 (400x lens) |
|
Immunohistochemistry of paraffin embedded mouse Skeletal muscle using P27 (GB11154) at dilution of 1:500 (400x lens) |
|
Immunohistochemistry of paraffin embedded rat Skeletal muscle using P27 (GB11154) at dilution of 1:500 (400x lens) |
|
Immunofluorescence of paraffin embedded mouse heart using P27 (GB11154) at dilution of 1:400 (400x lens) |
|
Immunofluorescence of paraffin embedded rat colon using P27 (GB11154) at dilution of 1:400 (400x lens) |
|
Immunofluorescence of paraffin embedded rat hepatitis using P27 (GB11154) at dilution of 1:400 (400x lens) |
|
Immunofluorescence of paraffin embedded rat nephritis using P27 (GB11154) at dilution of 1:400 (400x lens) |
|
Immunofluorescence of paraffin embedded rat pneumonia using P27 (GB11154) at dilution of 1:400 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室