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Anti -BRSK1 Rabbit pAb

价格: 在线咨询
货号:
KT011813
产品规格:
100 μL
Applications:
WB
Species:
M
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

BRSK1 rabbit polyclonal antibody

Protein full name

Serine/threonine-protein kinase BRSK1

Synonyms

Brain-specific serine/threonine-protein kinase 1, BR serine/threonine-protein kinase 1, Serine/threonine-protein kinase SAD-B, Brsk1, Gm1100, Sadb

Immunogen

Recombinant protein corresponding to Mouse BRSK1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

85 kDa

Observed MW.

90 kDa

Uniprot ID

Q5RJI5




Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse

1: 500-1: 1000

brain, cerebral cortex, cerebellum, hippocampus, testis, ovary




Background

BRSK1 was initially identified as a mammalian homolog to the fission yeast S. pombe Cdr2, a mitosis-regulatory kinase and also shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. Similar to its yeast homolog, BRSK1 is thought to be involved in stress-induced cell cycle arrest. Overexpression of this protein leads to the G2/M arrest in HeLa S2 cells and UV-induced G2/M arrest could be partially abrogated by reduced expression of BRSK1 through the use of siRNA, indicating its role in DNA damage checkpoint function. More recently, it has been shown that both BRSK1 and the related protein BRSK2 are required for mammalian neuronal polarization.




Images


Picture 1.png Western blot analysis of BRSK1 (GB111548) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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