欢迎,来到万物生物官方网站!
邮箱:355185756@qq.com
全国服务热线: 400-1016-218

Anti -Cytokeratin 1 Rabbit pAb

价格: 在线咨询
货号:
KT011902
产品规格:
100ul
Applications:
WB
Species:
H/M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Cytokeratin 1 rabbit polyclonal antibody

Protein full name

Keratin, type II cytoskeletal 1

Synonyms

67 kDa cytokeratin, Cytokeratin-1, Keratin-1, CK-1, K1, Type-II keratin Kb1, Krt1, Krt2-1, EHK1, Keratin type II cytoskeletal 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Cytokeratin 1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

66 kDa

Observed MW.

66 kDa

Uniprot ID

P04264, P04104, Q6IMF3




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

skin




Background


Cytokeratin 1 is a heterotetramer of two type I as well as two type II keratins localized in the cell membrane and is generally associated with keratin-10 . It has been suggested to regulate the activity of kinases such as PKC/SRC via binding to integrin beta-1 and the receptor of activated protein kinase C. Cytokeratin 1 and its heterodimer partner KRT10 are the major constituents of 4 intermediate filament cytoskeleton in suprabasal epidermis/keratinocytes, and their upregulation precedes expression of filaggrin and cornified envelope proteins. Covalent crosslinking of cytokeratin 1 but not of KRT10 to these proteins, in addition to a complex series of lipids, ultimately forms the cornified/lipid envelope, that constitutes the epidermal barrier together with Langerhans cells.




Images


Picture 1.png

Western blot analysis of cytokeratin-1 (GB111017) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


凡合肥万物生物科技有限公司销售的产品均有严格的质量保证。如发现产品存在包装规格疑问,请于收货之日起七日内向我公司总部或当地办事处提出,并请保证该产品,以备本公司进行核对检验。如果发现有质量问题,请于收货后一月内保留产品50%以上的量,以便本公司回收产品进行质检,确认产品质量。如逾期,则视为已经对本公司产品进行验收。 声明:如发生产品索赔事宜,本公司仅在产品价格范围内酌情赔偿,恕不接受超出产品价格范围之赔偿。客户在使用过程中有任何技术问题可以拨打技术售后服务电话我们随时给予解答。

合肥万物生物科技有限公司

客服热线:400-1016-218

QQ:355185756

地址:安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室

服务热线

400-1016-218

功能和特性

价格和优惠

获取新资料

售后服务

咨询微信