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产品详情
操作说明
注意事项
Product Information
|
Description |
RAB7 rabbit polyclonal antibody |
|
Protein full name |
Ras-related protein Rab-7a |
|
Synonyms |
Rab7a, RAB7 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse RAB7 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
23 kDa |
|
Observed MW. |
23 kDa |
|
Uniprot ID |
P51149, P51150, P09527 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
kidney, lung |
Background
Key regulator in endo-lysosomal trafficking. Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades. Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events.Also involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes, pathogen-induced phagosomes (or vacuoles) and autophagosomes. Plays a role in the maturation and acidification of phagosomes that engulf pathogens. Plays a role in the fusion of phagosomes with lysosomes. Plays important roles in microbial pathogen infection and survival, as well as in participating in the life cycle of viruses. In concert with RAC1, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts.
Images
|
|
Western blot analysis of RAB7A (GB111190) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室