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Anti -Lipocalin-2 / NGAL Rabbit pAb

价格: 在线咨询
货号:
KT011984
产品规格:
100ul
Applications:
IHC/IF
Species:
H
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

NGAL rabbit polyclonal antibody

Protein full name

Neutrophil gelatinase-associated lipocalin

Synonyms

NGAL, Lipocalin-2, Oncogene 24p3, Siderocalin, p25

Immunogen

Recombinant protein corresponding to Human NGAL

Isotype

IgG

Purity

Affinity purification

Subcellular location

Secreted

Uniprot ID

P80188




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human

1: 500-1: 3000

colon, liver, liver cancer, lung, lung cancer




Background


Lipocalin 2 is a member of the lipocalin family, It involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5- DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis.




Images


Picture 1.png

Immunohistochemistry of paraffin embedded human liver using NGAL (GB111134) at dilution of 1:1000 (400x lens)

Picture 2.png

Immunohistochemistry of paraffin embedded human liver cancer using NGAL (GB111134) at dilution of 1:1000 (400x lens)

Picture 3.png

Immunohistochemistry of paraffin embedded human lung using NGAL (GB111134) at dilution of 1:1000 (400x lens)

Picture 4.png

Immunohistochemistry of paraffin embedded human lung cancer using NGAL (GB111134) at dilution of 1:1000 (400x lens)

Picture 5.png

Immunofluorescence of paraffin embedded human colon using NGAL (GB111134) at dilution of 1:2000 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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