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Anti -GRK2 Rabbit pAb

价格: 在线咨询
货号:
KT012012
产品规格:
Applications:
WB
Species:
H,M
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

GRK2 rabbit polyclonal antibody

Protein full name

Beta-adrenergic receptor kinase 1

Synonyms

Beta-ARK-1, G-protein-coupled receptor kinase 2, Grk2, Adrbk1

Immunogen

Recombinant protein corresponding to Mouse GRK2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

80 kDa

Observed MW.

80 kDa

Uniprot ID

P25098, Q99MK8




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse

1: 500-1: 1000

spleen, lymph nodes




Background


The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.




Images


Picture 1.png

Western blot analysis of grk2 (GB111115) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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