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Anti -EFTUD2 Rabbit pAb

价格: 在线咨询
货号:
KT012064
产品规格:
100 μL
Applications:
WB/IHC/IF
Species:
HMR/HMR
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

EFTUD2 rabbit polyclonal antibody

Protein full name

116 kDa U5 small nuclear ribonucleoprotein component

Synonyms

Snrp116, Elongation factor Tu GTP-binding domain-containing protein 2, U5-116 kDa, U5 snRNP-specific protein,116 kDa,  EFTUD2

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse EFTUD2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Predicted MW.

109 kDa

Observed MW.

130 kDa

Uniprot ID

Q15029, O08810




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

brain, liver

IHC/IF

Human, Mouse, Rat

1: 500-1: 3000

brain, colon cancer, liver, lung, lung cancer, ovarian cancer, ovary, testis




Background

EFTUD2 encodes the 116 kDa U5 small nuclear ribonecleoprotein (snRNP) component, also named SNU114, it has GTP binding activity and is required for pre-mRNA splicing. Evolutionarily conserved human snRNP protein (U5-116kDa) is homologous to the ribosomal elongation factor EF-2 (ribosomal translocase). Defects in EFTUD2 are the cause of mandibulofacial dysostosis with microcephaly (MFDM).




Images


Picture 1.png

Western blot analysis of EFTUD2 (GB111188) at dilution of 1: 500

Picture 2.png

Immunohistochemistry of paraffin embedded human colon cancer using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens)

Picture 3.png

Immunohistochemistry of paraffin embedded human lung cancer using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens)

Picture 4.png

Immunohistochemistry of paraffin embedded mouse brain using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens)

Picture 5.png

Immunohistochemistry of paraffin embedded mouse lung using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens)

Picture 6.png

Immunohistochemistry of paraffin embedded rat brain using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens)

Picture 7.png

Immunohistochemistry of paraffin embedded rat lung using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens)

Picture 8.png

Immunohistochemistry of paraffin embedded rat ovary using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens)

Picture 9.png

Immunofluorescence of paraffin embedded human ovarian cancer using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens)

Picture 10.png

Immunofluorescence of paraffin embedded mouse liver using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens)

Picture 11.png

Immunofluorescence of paraffin embedded mouse lung using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens)

Picture 12.png

Immunofluorescence of paraffin embedded rat brain using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens)

Picture 13.png

Immunofluorescence of paraffin embedded rat testis using EFTUD2 (GB111188) at dilution of 1: 2400 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025)

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