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Anti -KAT5 / Tip60 Rabbit pAb

价格: 在线咨询
货号:
KT012140
产品规格:
100 μL
Applications:
IHC/IF
Species:
H,M,R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Tip60 rabbit polyclonal antibody

Protein full name

Histone acetyltransferase KAT5

Synonyms

60 kDa Tat-interactive protein, Tip60, Histone acetyltransferase HTATIP, Kat5, Lysine acetyltransferase 5, Htatip, Tip60

Immunogen

Recombinant protein corresponding to Mouse Tip60

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

Q92993, Q8CHK4, Q99MK2




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1: 500-1: 3000

brain, breast cancer, heart, hippocampus, kidney, liver, lung cancer, testis




Background


Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair.




Images


Picture 1.png

Immunohistochemistry of paraffin embedded human breast cancer using TIP60 (GB111065) at dilution of 1:1000 (400x lens)

Picture 2.png

Immunohistochemistry of paraffin embedded human lung cancer using TIP60 (GB111065) at dilution of 1:2000 (400x lens)

Picture 3.png Immunohistochemistry of paraffin embedded mouse brain using TIP60 (GB111065) at dilution of 1:1000 (400x lens)
Picture 4.png Immunohistochemistry of paraffin embedded mouse brain using TIP60 (GB111065) at dilution of 1:2000 (400x lens)
Picture 5.png Immunohistochemistry of paraffin embedded mouse heart using TIP60 (GB111065) at dilution of 1:2000 (400x lens)
Picture 6.png Immunohistochemistry of paraffin embedded rat brain using TIP60 (GB111065) at dilution of 1:2000 (400x lens)
Picture 7.png Immunohistochemistry of paraffin embedded rat testis using TIP60 (GB111065) at dilution of 1:2000 (400x lens)
Picture 8.png Immunofluorescence of paraffin embedded mouse heart using TIP60 (GB111065) at dilution of 1:2000 (400x lens)
Picture 9.png Immunofluorescence of paraffin embedded mouse hippocampus using TIP60 (GB111065) at dilution of 1:2000 (400x lens)
Picture 10.png Immunofluorescence of paraffin embedded mouse hippocampus using TIP60 (GB111065) at dilution of 1:2000 (400x lens)
Picture 11.png Immunofluorescence of paraffin embedded mouse kidney using TIP60 (GB111065) at dilution of 1:2000 (400x lens)

Picture 12.png

Immunofluorescence of paraffin embedded mouse kidney using TIP60 (GB111065) at dilution of 1:2000 (400x lens)
Picture 13.png Immunofluorescence of paraffin embedded mouse liver using TIP60 (GB111065) at dilution of 1:2000 (400x lens)
Picture 14.png Immunofluorescence of paraffin embedded rat hippocampus using TIP60 (GB111065) at dilution of 1:2000 (400x lens)

Picture 15.png

Immunofluorescence of paraffin embedded rat testis using TIP60 (GB111065) at dilution of 1:2000 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).



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