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Anti -mTOR Rabbit pAb

价格: 在线咨询
货号:
KT012202
产品规格:
100 μL
Applications:
WB
Species:
HMR
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

mTOR rabbit polyclonal antibody

Protein full name

Serine/threonine-protein kinase mTOR

Synonyms

FK506-binding protein 12-rapamycin complex-associated protein 1, Mammalian target of rapamycin, Rapamycin target protein 1, FRAP, FRAP1, FRAP2, RAFT1, RAPT1, mTOR

Immunogen

Recombinant protein corresponding to Mouse mTOR

Isotype

IgG

Purity

Affinity purification

Predicted MW.

289 kDa

Observed MW.

289 kDa

Uniprot ID

P42345, Q9JLN9, P42346



Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

testis, liver, brain



Background


Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis.

   



Images



Western blot analysis of mTOR (GB11405) at dilution of 1: 500


Western blot analysis of mTOR (GB11405) at dilution of 1: 500




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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