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Anti -Frizzled 6 Rabbit pAb

价格: 在线咨询
货号:
KT012214
产品规格:
100 μL
Applications:
WB
Species:
M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Frizzled 6 rabbit polyclonal antibody

Protein full name

Frizzled-6

Synonyms

Fz-6, mFz6, Fzd6, NDNC10, Frizzled homolog 6, Frizzled family receptor 6, Frizzled 6 seven transmembrane spanning receptor, hFz6

Immunogen

Recombinant protein corresponding to Mouse Frizzled 6

Isotype

IgG

Purity

Affinity purification

Predicted MW.

79 kDa

Observed MW.

72 kDa

Uniprot ID

Q61089




Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 1000-1: 2000

liver, kidney, prostate, pancreas




Background


This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis.




Images


Picture 1.png

Western blot analysis of Frizzled-6 (GB112220) at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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