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Anti -GSK3 alpha Rabbit pAb

价格: 在线咨询
货号:
KT011236
产品规格:
100ul
Applications:
IHC/IF
Species:
M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

GSK3 alpha rabbit polyclonal antibody

Protein full name

Glycogen synthase kinase-3 alpha

Synonyms

GSK-3 alpha, Serine/threonine-protein kinase GSK3A, Gsk3a

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse GSK3 alpha

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

Q2NL51, P18265




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Mouse, Rat

1: 500-1: 3000

colon, epencephalon, heart, small intestine, spleen, thymus, brain




Background


Glycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily; GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis.




Images


Immunohistochemistry of paraffin embedded mouse colon using GSK-3A at dilution of 1:2200 (400x lens)

Immunohistochemistry of paraffin embedded mouse epencephalon using GSK-3A at dilution of 1:2200 (400x lens)

Immunohistochemistry of paraffin embedded mouse heart using GSK-3A  at dilution of 1:2200 (400x lens)

Immunohistochemistry of paraffin embedded mouse spleen using GSK-3A at dilution of 1:2200 (400x lens)

Immunohistochemistry of paraffin embedded mouse thymus using GSK-3A at dilution of 1:2200 (400x lens)

Immunohistochemistry of paraffin embedded rat brain using GSK-3Aat dilution of 1:2200 (400x lens)

Immunohistochemistry of paraffin embedded rat epencephalon using GSK-3A at dilution of 1:2200 (400x lens)

Immunohistochemistry of paraffin embedded rat spleen using GSK-3A  at dilution of 1:2200 (400x lens)

Immunohistochemistry of paraffin embedded rat thymus using GSK-3A at dilution of 1:2200 (400x lens)

Immunofluorescence of paraffin embedded mouse epencephalon using GSK-3Aat dilution of 1:2200 (400x lens)

Immunofluorescence of paraffin embedded mouse heart using GSK-3Aat dilution of 1:2200 (400x lens)

Immunofluorescence of paraffin embedded mouse small intestine using GSK-3A at dilution of 1:2200 (400x lens)

Immunofluorescence of paraffin embedded rat brain using GSK-3A at dilution of 1:2200 (400x lens)

Immunofluorescence of paraffin embedded rat spleen using GSK-3A at dilution of 1:2200 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


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