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Anti -Collagen I Rabbit pAb
价格：
在线咨询
货号：
DRF10163
产品规格：
100 μL
Applications：
IHC/IF
Species：
H/M/R,H/M/R
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
Collagen I rabbit polyclonal |
|
Protein full name |
Collagen alpha-1(I) chain |
|
Synonyms |
COL1A1, EDSC, OI1, OI2, OI3, OI4, collagen type I alpha 1, collagen type I alpha 1 chain |
|
Immunogen |
Recombinant protein corresponding to Mouse COL1A1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
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Uniprot ID |
Applications
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Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Human, Mouse, Rat |
1: 800-1: 1600 |
para-cancer kidney, skin, fibrosis liver, lung |
|
IF |
Human, Mouse, Rat |
1: 800-1: 1600 |
atherosclerotic vessels, liver, lung, para-cancer lung |
Background
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.
Images
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Immunohistochemistry analysis of paraffin-embedded human para-cancer kidney using Collagen I (GB11022-3) at dilution of 1: 1600 |
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Immunohistochemistry analysis of paraffin-embedded mouse skin using Collagen I (GB11022-3) at dilution of 1: 1600
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Immunohistochemistry analysis of paraffin-embedded mouse fibrosis liver using Collagen I (GB11022-3) at dilution of 1: 1600
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Immunohistochemistry analysis of paraffin-embedded rat fibrosis liver using Collagen I (GB11022-3) at dilution of 1: 1600 |
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Immunohistochemistry analysis of paraffin-embedded rat lung using Collagen I (GB11022-3) at dilution of 1: 1600 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse lung using Collagen I (GB11022-3) at dilution of 1: 1600 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse atherosclerotic vessels using Collagen I (GB11022-3) at dilution of 1: 1600 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat liver using Collagen I (GB11022-3) at dilution of 1: 1600 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat lung using Collagen I (GB11022-3) at dilution of 1: 1600 |
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Immunofluorescent analysis of paraformaldehyde-fixed human para-cancer lung using COLIII (GB11629) (green) + Collagen I (GB11022-3) (red) + Actin (GB111364) (yellow) + CD31 (GB12064) (orange) at dilution of 1: 1600 |
|
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Immunofluorescent analysis of paraformaldehyde-fixed mouse BDL model liver using Collagen I (GB11022-3) at dilution of 1: 1600 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
Publications:
|
|
Title |
Journal |
Pubmed ID |
Application |
|
1 |
An injectable liposome for sustained release of tanshinone IIA to the treatment of acute blunt muscle injury by augmenting autophagy and alleviating oxidative stress. |
American Journal of Translational Research |
32913497 |
IHC |
|
2 |
Twist1-induced miR-199a-3p promotes liver fibrosis by suppressing caveolin-2 and activating TGF-β pathway. |
Signal Transduction and Targeted Therapy |
32499481 |
IHC |
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室