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Anti -F4/80 Rabbit pAb

价格: 在线咨询
货号:
DRF10166
产品规格:
100 μL
Applications:
IHC/IF
Species:
M/R,M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

F4/80 rabbit polyclonal

Protein full name

Adhesion G protein-coupled receptor E1

Synonyms

ADGRE1,TM7LN3,EMR1,Gpf480,

adhesion G protein-coupled receptor E1

Immunogen

Recombinant protein corresponding to 

Mouse F4/80 

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane

Uniprot ID

Q61549



Applications


applications

species

dilution

Positive tissue

IHC

Mouse, Rat

1: 1000-1: 2000

liver, lung

IF

Mouse, Rat

1: 500-1: 2000

lymph node, septic liver



Background


EGF-like module-containing mucin-like hormone receptor-like 1 also known as F4/80 is a proteinencoded by the ADGRE1 gene. EMR1 is a member of the adhesion GPCR family.Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.




Images



Immunohistochemistry analysis of paraffin-embedded mouse liver using F4/80 (GB11027) at dilution of 1: 1500


Immunohistochemistry analysis of paraffin-embedded mouse lung using F4/80 (GB11027) at dilution of 1: 1500

Immunofluorescent analysis of paraformaldehyde-fixed mouse septic liver using F4/80 (GB11027) at dilution of 1: 1000


Immunofluorescent analysis of paraformaldehyde-fixed mouse lymph node using F4/80 (GB11027) at dilution of 1: 1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


Publications:



Title

Journal

Pubmed ID

Application

1

Spermidine improves gut barrier integrity and gut microbiota function in diet-induced obese mice.

Gut Microbes

33151120

IF

2

High-fat diet-induced obesity affects alpha 7 nicotine acetylcholine receptor expressions in mouse lung myeloid cells.

Scientific Reports

33110180

IF

3

Overexpressing TGF-β1 in mesenchymal stem cells attenuates organ dysfunction during CLP-induced septic mice by reducing macrophage-driven inflammation.

Stem Cell Research & Therapy

32883356

IHC

4

High-fat diet-induced adipose tissue expansion occurs prior to insulin resistance in C57BL/6J mice.

Chronic Diseases and Translational Medicine

32885155

IHC

5

Anti-inflammatory properties of uvaol on DSS-induced colitis and LPS-stimulated macrophages

Chinese Medicine

32411289

IHC

6

Gaudichaudione H Inhibits Inflammatory Responses in Macrophages and Dextran Sodium Sulfate-Induced Colitis in Mice.

Frontiers in Pharmacology

32009962

IHC

7

Gdf11 gene transfer prevents high fat diet-induced obesity and improves metabolic homeostasis in obese and STZ-induced diabetic mice.

Journal of Translational Medicine

31847906

IHC

8

Chronic effects of repeated low-dose cisplatin treatment in mouse kidneys and renal tubular cells.

American Journal of Physiology - Renal Physiology

31532246

IHC

9

Safranal Alleviates Dextran Sulfate Sodium-Induced Colitis and Suppresses Macrophage-Mediated Inflammation

Frontiers in Pharmacology

31736758

IHC

10

Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF- β 1/Smad3 and TGF- β 1/p38 MAPK Pathways

Mediators of Inflammation

31467486

IHC


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