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Anti -Claudin 1 Rabbit pAb

价格: 在线咨询
货号:
DRF10169
产品规格:
100 μL
Applications:
IHC/IF
Species:
M/R,M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description Claudin 1 rabbit polyclonal
Protein full name Claudin-1
Synonyms CLDN1, CLD1, ILVASC, SEMP1, claudin 1
Immunogen KLH conjugated Synthetic peptide
corresponding to Mouse claudin-1
Isotype IgG
Purity Affinity purification
Subcellular location Cell junction, Cell membrane,
Basolateral cell membrane
Uniprot ID O88551




Applications


Applications Species Dilution Positive Tissue
IHC Mouse, Rat 1: 200-1: 800 liver,lung,colon
IF Mouse, Rat 1: 400-1: 800 liver,lung,colon




Background


Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.





Images



Immunohistochemistry analysis of paraffin-embedded mouse liver using Clauind 1(GB11032) at dilution of 1: 400

Immunohistochemistry analysis of paraffin-embedded mouse colon using Clauind 1 (GB11032) at dilution of 1: 400

Immunohistochemistry analysis of paraffin-embedded mouse lung using Clauind 1 (GB11032) at dilution of 1: 400




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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