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产品详情
操作说明
注意事项
Product Information
|
Description |
CD68 rabbit polyclonal |
|
Protein full name |
Macrosialin |
|
Synonyms |
CD68,CD68 Molecule,Scavenger Receptor Class D, Member 1 ,Macrophage Antigen CD68,GP110 ,Macrosialin,SCARD1, LAMP4 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CD68 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Uniprot ID |
Applications
|
applications |
species |
dilution |
Positive tissue |
|
IHC |
Mouse, Rat |
1: 300-1: 1000 |
hepatitis, spleen, lung, liver |
|
IF |
Mouse, Rat |
1: 500-1: 1000 |
spleen |
Background
Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse hepatitis using CD68 (GB11067) at dilution of 1: 500 |
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Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD68 (GB11067) at dilution of 1: 500
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Immunohistochemistry analysis of paraffin-embedded mouse lung using CD68 (GB11067) at dilution of 1: 500 |
|
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Immunohistochemistry analysis of paraffin-embedded mouse liver using CD68 (GB11067) at dilution of 1: 500 |
|
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Immunofluorescent analysis of paraformaldehyde-fixed rat spleen using CD68 (GB11067) at dilution of 1: 500 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse bone using CD68(GB11067) at dilution of 1:1000 |
|
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Immunohistochemistry analysis of paraffin-embedded rat lymph node using CD68(GB11067) at dilution of 1:1000 |
|
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Immunohistochemistry analysis of paraffin-embedded rat spleen using CD68(GB11067) at dilution of 1:1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
Publications:
|
|
Title |
Journal |
Pubmed ID |
Application |
|
1 |
Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy. |
Redox Biology |
33152664 |
IHC |
|
2 |
Single-cell RNA-Seq reveals the transcriptional landscape and heterogeneity of skin macrophages in Vsir-/- murine psoriasis. |
Theranostics |
32929361 |
IHC |
|
3 |
Anti-Atherosclerosis Effect of Angong Niuhuang Pill via Regulating Th17/Treg Immune Balance and Inhibiting Chronic Inflammatory on ApoE-/- Mice Model of Early and Mid-Term Atherosclerosis. |
Frontiers in Pharmacology |
32082145 |
IHC |
|
4 |
Gaudichaudione H Inhibits Inflammatory Responses in Macrophages and Dextran Sodium Sulfate-Induced Colitis in Mice. |
Frontiers in Pharmacology |
32009962 |
IHC |
|
5 |
Human amnion mesenchymal stem cells attenuate atherosclerosis by modulating macrophage function to reduce immune response. |
International Journal of Molecular Medicine |
31364743 |
IHC |
|
6 |
IL-17A Can Promote Propionibacterium acnes-Induced Sarcoidosis-Like Granulomatosis in Mice. |
Frontiers in Immunology |
31474992 |
IHC |
|
7 |
C1q/TNF-related protein-9 promotes macrophage polarization and improves cardiac dysfunction after myocardial infarction. |
Journal of Cellular Physiology |
30953351 |
IF |
|
8 |
Galectin-3 Mediates Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension. |
Aging and Disease |
31440380 |
IHC |
|
9 |
Carotid baroreceptor stimulation in obese rats affects white and brown adipose tissues differently in metabolic protection. |
Journal of Lipid Research |
31126973 |
IHC |
|
10 |
CXCL12/CXCR4 promotes inflammation-driven colorectal cancer progression through activation of RhoA signaling by sponging miR-133a-3p. |
Journal of Experimental & Clinical Cancer Research : CR |
30678736 |
IHC/IF |
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客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室