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产品详情
操作说明
注意事项
Product Information
|
Description |
IL-1 beta rabbit polyclonal |
|
Protein full name |
Interleukin-1 beta |
|
Synonyms |
IL1B, IL-1, IL1-BETA, IL1F2, interleukin 1 beta |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to human IL-1β |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Human, Mouse, Rat |
1:800-1:1600 |
tonsillitis, pneumonia, inflammation lung, splenitis |
|
IF |
Human, Mouse, Rat |
1:800-1:1600 |
lung |
Background
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells.
Images
|
|
Immunohistochemistry analysis of paraffin-embedded human tonsillitis using IL-1β (GB11113) at dilution of 1: 800 |
|
|
Immunohistochemistry analysis of paraffin-embedded mouse pneumonia using IL-1β (GB11113) at dilution of 1: 800 |
|
|
Immunohistochemistry analysis of paraffin-embedded mouse inflammation lung using IL-1β (GB11113) at dilution of 1: 800 |
|
|
Immunohistochemistry analysis of paraffin-embedded rat splenitis using IL-1β (GB11113) at dilution of 1: 800 |
|
|
Immunofluorescent analysis of paraformaldehyde-fixed rat lung with LPS treated for 24h using IL-1β (GB11113) at dilution of 1: 800 |
|
|
Immunofluorescent analysis of paraformaldehyde-fixed mouse lung with LPS treated for 6husing IL-1β (GB11113) at dilution of 1: 800
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
Publications:
|
|
Title |
Journal |
Pubmed ID |
Application |
|
1 |
Early Enteral Nutrition Preserves Intestinal Barrier Function through Reducing the Formation of Neutrophil Extracellular Traps (NETs) in Critically Ill Surgical Patients. |
Oxidative Medicine and Cellular Longevity |
33294125 |
IHC |
|
2 |
Long-term inhibition of dipeptidyl-peptidase 4 reduces islet infiltration and downregulates IL-1β and IL-12 in NOD mice. |
International Immunopharmacology |
33182020 |
IHC |
|
3 |
QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism. |
Cell Death & Disease |
32382069 |
IHC |
|
4 |
Induction of pathological changes and impaired expression of cytokines in developing female rat spleen after chronic excess fluoride exposure. |
Toxicology and Industrial Health |
30463494 |
IHC |
|
5 |
Inhibition of endoplasmic reticulum stress by 4-phenylbutyric acid prevents vital organ injury in rat acute pancreatitis. |
American Journal of Physiology - Gastrointestinal and Liver Physiology |
30138574 |
IF |
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室