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Anti - E Cadherin Rabbit pAb

价格: 在线咨询
货号:
DRF10197
产品规格:
100 μL
Applications:
WB/IHC
Species:
H/M/R,H/M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

E Cadherin rabbit polyclonal

Protein full name

Cadherin-1

Synonyms

CDH1, Arc-1, CD324, CDHE, ECAD,

LCAM, UVO, cadherin 1,

Epithelial Cadherin,E-Cadherin,CAM 120/80

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse E Cadherin 

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane, Cytoplasm

Predicted MW.

98 kDa

Observed MW.

135 kDa

Uniprot ID

P12830P09803Q9R0T4




Applications


applications

species

dilution

Positive tissue

WB

Human, Mouse, Rat

1: 1000-1: 2000

spleen, lung, kidney

IHC

Human, Mouse, Rat

1: 500-1: 1000

liver, stomach, colon

IF

Human, Mouse, Rat

1: 200-1: 1500

uterus, colon, stomach



Background


Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.




Images


Western blot analysis of E Cadherin (GB11082) at dilution of 1: 1000

Western blot analysis of E Cadherin (GB11082) at dilution of 1: 1000


Immunohistochemistry analysis of paraffin-embedded human liver using 

E Cadherin (GB11082) at dilution of 1: 1000


Immunohistochemistry analysis of paraffin-embedded human liver using 

E Cadherin (GB11082) at dilution of 1: 1000


Immunohistochemistry analysis of paraffin-embedded mouse liver using E Cadherin (GB11082) at dilution of 1: 500

Immunohistochemistry analysis of paraffin-embedded human prostate using E Cadherin (GB11082) at dilution of 1: 500

Immunohistochemistry analysis of paraffin-embedded mouse stomach using E Cadherin (GB11082) at dilution of 1: 1000


Immunohistochemistry analysis of paraffin-embedded rat colon using E Cadherin (GB11082) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed mouse uterus using 

E Cadherin (GB11082) at dilution of 1: 500


Immunofluorescent analysis of paraformaldehyde-fixed mouse colon  using E Cadherin (GB11082) at dilution of 1: 500

Immunofluorescent analysis of paraformaldehyde-fixed rat stomach using 

E Cadherin (GB11082) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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