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Anti -L1CAM Rabbit pAb
价格：
在线咨询
货号：
DRF101119
产品规格：
100 μL
Applications：
WB/IHC/IF
Species：
M/R,M/R,M/R
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
L1CAM rabbit polyclonal |
|
Protein full name |
Neural cell adhesion molecule L1 |
|
Synonyms |
NCAM-L1, CD171, L1cam, Caml1, CD171 antigen, HSAS, MASA |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse L1CAM |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Predicted MW. |
141 kDa |
|
Observed MW. |
141/220 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
brain, cerebral cortex, hippocampus, spinal cord |
|
IHC |
Mouse, Rat |
1: 1000-1: 4000 |
thalamus, brain, cerebellum |
|
IF |
Mouse, Rat |
1: 500-1: 1000 |
thalamus, brain, cerebellum |
Background
The protein encoded by L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of L1CAM results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.
Images
|
|
Western blot analysis of L1CAM (GB111004) at dilution of 1: 1000 Lane 1: Mouse brain tissue lysate Lane 2: Mouse cerebral cortex tissue lysate Lane 3: Mouse hippocampus tissue lysate Lane 4: Mouse spinal cord tissue lysate Lane 5: Rat brain tissue lysate Lane 6: Rat cerebral cortex tissue lysate Lane 7: Rat hippocampus tissue lysate |
|
|
Immunohistochemistry analysis of paraffin-embedded mouse thalamus using L1CAM (GB111004) at dilution of 1: 2000 |
|
|
Immunohistochemistry analysis of paraffin-embedded rat cerebellum using L1CAM (GB111004) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室