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Anti -Synaptopodin Rabbit pAb

价格: 在线咨询
货号:
DRF101167
产品规格:
100 μL
Applications:
WB
Species:
M/R
购买数量:
在线咨询 400-1016-218
产品详情 操作说明 注意事项

Product Information


Description

Synaptopodin rabbit polyclonal

Protein full name

Synaptopodin

Synonyms

Synpo, Kiaa1029

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse Synaptopodin

Isotype

IgG

Purity

Affinity purification

Predicted MW.

100 kDa

Observed MW.

100 kDa

Uniprot ID

Q8CC35, Q9Z327




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

brain, cerebral cortex




Background


SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene for synaptopodin do not form a spine apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.




Images


image.png

Western blot analysis of Synaptopodin (GB111049) at dilution of 1: 1000

Lane 1: Mouse brain tissue lysate

Lane 2: Mouse cerebral cortex tissue lysate

Lane 3: Rat brain tissue lysate

Lane 4: Rat cerebral cortex tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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