服务热线
400-1016-218
联系方式
- 手机：400-1016-218
- Q Q：355185756
- 邮箱：355185756@qq.com
- 地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室
Anti -cIAP2 Rabbit pAb
价格：
在线咨询
货号：
DRF101170
产品规格：
100 μL
Applications：
WB/IHC/IF
Species：
M/R,M/R,M/R
购买数量：
在线咨询
400-1016-218
产品详情
操作说明
注意事项
Product Information
|
Description |
cIAP2 rabbit polyclonal |
|
Protein full name |
Baculoviral IAP repeat-containing protein 3 |
|
Synonyms |
Cellular inhibitor of apoptosis 2, C-IAP2, Birc3, Inhibitor of apoptosis protein 1, mIAP1, RING-type E3 ubiquitin transferase BIRC3 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse cIAP2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
|
|
Predicted MW. |
67 kDa |
|
Observed MW. |
67 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
thymus, testes, lymph nodes |
|
IHC |
Mouse, Rat |
1: 1500-1: 3000 |
lung, testis, spleen |
|
IF |
Mouse, Rat |
1: 750-1: 1500 |
lung, testis, spleen |
Background
Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin- protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase dependent and caspase independent manner.
Images
|
Western blot analysis of cIAP2 (GB111051) at dilution of 1: 750 Lane 1: Mouse thymus tissue lysate Lane 2: Mouse lymph nodes tissue lysate Lane 3: Mouse testes tissue lysate Lane 4: Rat thymus tissue lysate |
|
Immunohistochemistry analysis of paraffin-embedded mouse lung using cIAP2 (GB111051) at dilution of 1: 3000 |
|
Immunohistochemistry analysis of paraffin-embedded mouse testis using cIAP2 (GB111051) at dilution of 1: 3000 |
|
Immunohistochemistry analysis of paraffin-embedded mouse spleen using cIAP2 (GB111051) at dilution of 1: 3000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
凡合肥万物生物科技有限公司销售的产品均有严格的质量保证。如发现产品存在包装规格疑问，请于收货之日起七日内向我公司总部或当地办事处提出，并请保证该产品，以备本公司进行核对检验。如果发现有质量问题，请于收货后一月内保留产品50%以上的量，以便本公司回收产品进行质检，确认产品质量。如逾期，则视为已经对本公司产品进行验收。 声明：如发生产品索赔事宜，本公司仅在产品价格范围内酌情赔偿，恕不接受超出产品价格范围之赔偿。客户在使用过程中有任何技术问题可以拨打技术售后服务电话我们随时给予解答。
合肥万物生物科技有限公司
客服热线：400-1016-218
QQ：355185756
地址：安徽省合肥市高新区黄山路602号合肥国家大学科技园A401室